Thursday, 14 February 2013 20:19

Denosumab reduced wrist fracture in postmenopausal women with osteoporosis

Written by 
Rate this item
(0 votes)

Upon further dissection of information from the FREEDOM trial, specialists affirmed that denosumab altogether upgraded sweep bone mineral thickness, mass and quality contrasted and placebo, plus altogether decreasing the danger for wrist crack.

See Also

Chance for break lessened by single implantation of zoledronic harsh corrosive ...

Odanacatib expanded BMD, bone quality in postmenopausal ...

Dark ladies screened, treated less for osteoporosis vs. white ...

Specialist James A. Simon, MD, CCD, NCMP, FACOG, of George Washington University, and partners resolved the impacts of denosumab (Prolia, Xgeva; Amgen) on span cortical and trabecular skeletal substance thickness, mass, quality and wrist break frequency from the study in which postmenopausal ladies with osteoporosis (n=7,808) appropriated placebo or denosumab 60 mg each 6 months for 36 months.

James A. Simon

Consistent with scientists, denosumab fundamentally expanded areal BMD and volumetric BMD, bone mineral substance and polar minute of inactivity vs. placebo (all P<.05).

Information additionally demonstrate that wrist break frequency was 2.9% for placebo and 2.5% for denosumab with a RR decrease of 16% (P=.21) at 36 months. Besides, patients with a femoral neck T-score of –2.5 or easier had an expanded hazard for wrist break. The specialists composed that denosumab fundamentally diminished the rate of wrist break (2.4%) contrasted and placebo (4%), with a RR decrease of 40% and a total danger decrease of 1.6% (P=.03).

As per the specialists, the aforementioned discoveries affirm formerly reported enhancements to sweep BMD after denosumab help in postmenopausal ladies with osteoporosis.

Divulgence: Several specialists report money related ties with Abbott, Agile Therapeutics, Amgen, Ascend Therapeutics, Azur Pharma, Bayer, BioSante Pharmaceuticals, Boehringer Ingelheim, Depomed, Eli Lilly, Endoceutics, Fabre-Kramer Pharmaceuticals, KV Pharmaceutical, Laboratoire HRA Pharma, Meditrina Pharmaceuticals, Merck, Merrion Pharmaceuticals, NDA Partners, Novartis, Novo Nordisk, Novogyne Pharmaceuticals, Nycomed, Pfizer, Polpharma, Roche, Sanofi-Aventis, Servier, Shionogi, Slate Pharmaceutical, Sprout Pharmaceuticals, Teva, Trovis Pharmaceuticals, United Osteoporosis Centers, Warner Chilcott, Watson Pharmaceuticals and Zentiva.

Read 35962 times

271 comments

  • Comment Link BarbaraDyese Monday, 22 January 2018 02:51 posted by BarbaraDyese

    usa online slots real money
    pogo casino slots
    free casino games vegas world
    free casino games slots no download

  • Comment Link Easy Payday Loan Saturday, 20 January 2018 17:44 posted by Easy Payday Loan

    loans instant approval best online loans instant approval instant loans online [url=http://loansinstantapproval.us.com]loans instant approval[/url]

  • Comment Link Miltonsoome Saturday, 20 January 2018 12:26 posted by Miltonsoome

    cheapest place get cialis
    cialis online
    order cialis at online pharmacy
    cialis online
    super cialis cheap
    generic cialis at walmart
    cheap cialis
    cialis generic
    cialis for sale online in canada

  • Comment Link DavidBrarf Friday, 19 January 2018 16:45 posted by DavidBrarf

    autocad 14 serial number cd key
    autodesk maya
    autocad 2011 64 bit windows 7 download
    autodesk revit
    autocad 2013 lt vs full version
    autocad download
    associated software sales autocad
    auto cad
    get autocad

  • Comment Link PearlSoype Thursday, 18 January 2018 23:27 posted by PearlSoype

    slots for money online
    online casino bovada
    456 free slots casino
    usa online slots real money

  • Comment Link CallieRhync Saturday, 13 January 2018 22:44 posted by CallieRhync

    payday loans no credit
    loans no credit
    payday loans no credit
    payday loans online no credit check

  • Comment Link SoniaPraft Thursday, 11 January 2018 00:07 posted by SoniaPraft

    free slots no download
    free slots online
    aol slots
    free online slots

  • Comment Link Kerrygek Tuesday, 09 January 2018 08:18 posted by Kerrygek

    casino games online
    free slots games
    free slot games
    free slots games

  • Comment Link Patrickapapy Tuesday, 09 January 2018 07:23 posted by Patrickapapy

    online casino real money
    free slots no download
    free casino games
    casino games slots free

  • Comment Link Judithgurgy Saturday, 06 January 2018 22:25 posted by Judithgurgy

    slots free
    online casinos
    slots for free
    free slots casino games

Leave a comment

Make sure you enter the (*) required information where indicated. HTML code is not allowed.